When and where:
Room E6519, Tuesday, Nov. 2, 12:15.
Jenn Wang from the Seydoux lab will be presenting:
Bucky ball organizes germ plasm assembly in zebrafish
Bontems, Stein, Marlow, Lyautey, Gupta, Mullins, and Dosch
Current Biology, 19:414-422
Jenn's comment on this paper selection:
"It's long been known that germ cell fate in many animals is specified by a specialized maternal cytoplasm, or germ plasm. However, the components of germ plasm and its assembly mechanisms are only recently beginning to be known. This paper shows that the Bucky ball protein is necessary for germ plasm assembly in zebrafish. Excitingly, they have some evidence that bucky ball may also be sufficient for germ cell formation. If I have time at the end, I will talk a little bit about our work on C. elegans germ granule partitioning, which has been thought to specify worm germ cells."
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