Monday, April 27, 2009

May 26 journal club

After a few postponements, Matt Beattie from the Zirkin lab will present on May 26 (!).
He will have a hard act to follow, after Chris added some zip to his April 14 presentation with highlights of Han Solo being frozen (and how about a few bonus points for the wookie imitator?) ... but Matt works on the aging male, so at least that has Harrison Ford as a common theme.

Matt will present:

Evidence that age-related changes in p38 MAP kinase contribute to the decreased steroid production by the adrenocortical cells from old rats, Aging Cell 7:168

Oxidative stress-induced inhibition of adrenal steroidogenesis requires participation of p38 mitogen-activated protein kinase signaling pathway, Journal of Endocrinology 198:193

Friday, April 10, 2009

April 14 journal club

NOTE: We will be back in Room W2303 on April 14.
Chris from the Matunis lab will be leading a discussion of:
Why these? ... Chris says:
"I chose this paper because it is one of very few reports that I am aware of demonstrating the role of an epigenetic regulator in the maintenance of mammalian germline stem cells. Although much work has been done regarding epigenetic modifications in differentiated germ cells, less is known about the role of epigenetic and chromatin modification in germline stem cell function. In our lab I am study the role of a chromatin remodeling complex, NURF, in the maintenance of Drosophila testis stem cells. Specifically, we are interested in understanding how chromatin remodeling factors contribute to the maintenance of stem cells within their endogenous niche including the role of the epigenetic state of a stem cell in its ability to interpret niche signals."